March 22, 2013

PCOS to Pregnancy: Multiples & Fertility Treatments

I remember wanting twins once in my life. I was about 7 years old and dreamed of being a mommy someday. I wanted twin girls, named Brittney and Whitney. Fast forward to today. I love being a mom to a little boy! While I wouldn't mind a little girl, I totally would be okay with all boys. As for the twin thing, oh boy! That sounds like a lot of work! Don't get me wrong, I'm sure we could manage it, but would I purposely choose to have twins? No way!

So why the twins talk? This has been a discussion in our home the past couple days. I just finished a round of Clomid. I'm pretty sure I ovulated based off of my charts and a few symptoms. I didn't have any ovulation tests on hand though. Last Friday, I went in for my "day 21" progesterone test. This checks my progesterone levels and indicates whether I ovulated or not. Normal range is considered 6.5 to 7, my level was 0.75. Not great! This is low, but not terrible news to me. The month I got pregnant with my son 2 years ago, my level was only 1.5 and my Dr. told me that I wouldn't get pregnant that month. I proved her wrong a couple weeks later with a positive pregnancy test.

My doctor's course of action is to double my dosage of Clomid next month. So instead of 50 mg a day, I will take 100 mg. This got me thinking about the chances of twins or other multiples. Here's the research that I found:

Twins are conceived naturally in about 2% of pregnancies. With fertility treatments, the statistic is about 40%. (source)

Twins: 1 in 10
Mulitples: 1 in 6.5

20% chance of twins or multiples

1 in 4

Women that are most likely to get pregnant with twins using fertility treatments:
White women in the 35-39 age range have a 1 in 37 chance
Black women in the 35-39 age range have a 1 in 32 chance

I wish the study on Clomid stated which dosage this was based on. Maybe it was an average. I don't have an elevated chance due to genetics. I also don't fall into the age range for women most likely to have twins. My husband is worried and doesn't want me to double the dose. Honestly, based on my last pregnancy success, it's possible I can still get pregnant on the 50 mg dosage, but I'm tired of waiting. I'm totally trusting that if I'm supposed to have twins, I will, and if I'm not, I won't! And hey, twins could be fun right? It would make up for all the time we've lost in trying to conceive by giving us two babies at once!

Did you get pregnant with twins or other multiples while using fertility treatments?

I'm Jenny, the mama behind the blog Cloth Diaper Revival.   I'm a stay at home mom to Noah and a wife to Chas, the cloth diapering dad.  I used to be a 3rd grade teacher until I was blessed with the birth of my first child, Noah. I'm currently trying to conceive my second child while struggling with infertility due to PCOS. This series covers my journey and my experiences along the way.


I appreciate your struggle as I was diagnosed with PCOS in my teens. I too was put on BCP around 14 in order to have regular cycles. I felt like a part of me died as my doctor explained the difficulties I would face later on in life when I tried to get pregnant. So at 20 (and still on the pill), I found myself surprisingly pregnant. I realized that about a month before I was battling a sinus infection and took a round of antibiotics. I wasn't great at taking the pill everyday let alone at the same time every day and I absentmindedly didn't think to use additional protection because the last time I was reminded not to mix antibiotics and BCP was probably 6 years prior! I ended up having a full-term pregnancy with no complications. My doctors thought I dodged a bullet.

The reason I write this comment to you is because as unorthodox as it may sound, I did some research on the topic of PCOS, BCP and antibiotics and found that some doctors actually recommend trying this method to conceive first before going down the clomid/metformin route.

At times I feel like I cheated some way because I didn't go through all the struggles like many do with PCOS but I can't help but share my story in case it actually helps someone out there! At the very least, it is always worth asking your doctor about.

I wish you the best in your journey for #2 and look forward to reading about it! Take care!

I've had 2 Clomid pregnancies. Both on 150 mg and also an HCG trigger shot. I still wasn't predictably ovulating on Clomid alone. One month I did release 3 viable eggs. Luckily, perhaps, I didn't get pregnant that month! Both of my pregnancies were singular - lost one, but got pregnant with my son on Clomid.

I also have PCOS, and before starting Clomid, my OB put me on 3 cycles of BCP to sort of "reset" me. My progesterone was also low every single time - even the two times I got pregnant. I immediately was started on progesterone suppositories with the second pregnancy, and i'm pretty sure it saved the pregnancy.

We had tried sort of passively for about a year on our own, but got pregnant on the third Clomid cycle (lost the baby at 9 weeks), then took 3 months off, and got pregnant on the fifth Clomid cycle. Like you, my RE told me that month looked bad and would probably be a wash (we were going to start IUI but because my lining looked too thick, we decided to just go with Clomid + HCG). But that's the month we conceived our son!

When we're ready to try for a second (if!), I hope it's as "quick." Although, when you're desperately trying to conceive, 5 months feels like an eternity!

Good luck!